Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710536 | 0.83 | HDAC3 (0.46) | SMN1; SMN2RXFP1MAPTTP53MEN1 | |
| SCHEMBL18073895 | 0.82 | ROCK2 (0.56) | SMN1; SMN2MAPTTP53ALDH1A1KDM4E | |
| SCHEMBL8554262 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL8555826 | 0.82 | KMT2A (0.44) | SMN1; SMN2TP53ALDH1A1GAAHPGD | |
| SCHEMBL7422734 | 0.81 | KDM4E (0.44) | PARP1RXFP1ALDH1A1GAAHSD17B10 | |
| SCHEMBL8629096 | 0.81 | MAPT (0.55) | RXFP1MAPTALDH1A1GAAHPGD | |
| SCHEMBL7416246 | 0.81 | ALOX5 (0.44) | SMN1; SMN2MAPTALDH1A1GAAHPGD | |
| SCHEMBL7707705 | 0.80 | SMN1; SMN2 (0.42) | PARP1SMN1; SMN2MAPTTP53ALDH1A1 | |
| SCHEMBL8553623 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2MAPTTP53ALDH1A1GAA | |
| SCHEMBL8557970 | 0.79 | MAPT (0.40) | SMN1; SMN2MAPTTP53ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |