Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13874336 | 0.76 | GRM1 (0.43) | FFAR2NR3C1GRM1HSD17B10RAB9A | |
| SCHEMBL16184434 | 0.76 | GRM1 (0.43) | FFAR2NR3C1GRM1HSD17B10KDM4E | |
| SCHEMBL7953771 | 0.75 | TSHR (0.43) | GRM1HSD17B10RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2420556 | 0.73 | PLA2G7 (0.47) | RAB9AKDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL391457 | 0.72 | ALDH1A1 (0.42) | RAB9AKDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL2726306 | 0.70 | NR3C1 (0.45) | FFAR2NR3C1GRM1RAB9AKDM4E | |
| SCHEMBL5249375 | 0.69 | NPC1 (0.68) | HSD17B10RAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL5554909 | 0.69 | KDM4E (0.38) | NR3C1RAB9AKDM4ENPC1TP53 | |
| SCHEMBL8235098 | 0.69 | NR3C1 (0.42) | FFAR2NR3C1GRM1HSD17B10RAB9A | |
| SCHEMBL14591145 | 0.69 | FFAR2 (0.49) | FFAR2NR3C1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830349-A1 | METHOD FOR PREPARING N, N'-DISUBSTITUED CYCLIC UREAS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-25 | — | — | EP | claimed |