Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557783 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASLC40A1EDNRB | |
| SCHEMBL8557399 | 0.88 | MAPT (0.49) | ALDH1A1MAPTLMNASLC40A1EDNRB | |
| SCHEMBL8556381 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNASLC40A1EDNRB | |
| SCHEMBL8557580 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASLC40A1EDNRB | |
| SCHEMBL8558989 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASLC40A1EDNRB | |
| SCHEMBL8557951 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNASLC40A1TSHR | |
| SCHEMBL8553792 | 0.84 | MAPT (0.40) | ALDH1A1MAPTLMNASLC40A1TSHR | |
| SCHEMBL8560073 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNASLC40A1EDNRB | |
| SCHEMBL8554218 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASLC40A1TSHR | |
| SCHEMBL8554061 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNASLC40A1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |