Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105863 | 0.66 | ALDH1A1 (0.46) | KMT2AMEN1MGLLALDH1A1KCNH2 | |
| SCHEMBL11528533 | 0.66 | KMO (0.53) | KMT2AMEN1MGLLALDH1A1MAPT | |
| SCHEMBL11535666 | 0.66 | KMO (0.53) | KMT2AMEN1MGLLALDH1A1MAPT | |
| SCHEMBL8109646 | 0.66 | MGLL (0.43) | KMT2AMEN1MGLLLMNAMAPT | |
| SCHEMBL8096311 | 0.65 | MGLL (0.42) | KMT2AMEN1MGLLLMNAMAPT | |
| SCHEMBL8155669 | 0.65 | LMNA (0.47) | KMT2AMEN1MGLLKCNH2LMNA | |
| SCHEMBL11262335 | 0.64 | MEN1 (0.49) | KMT2AMEN1MGLLALDH1A1LMNA | |
| SCHEMBL11531095 | 0.64 | POLB (0.59) | KMT2AMEN1CYP2C19MGLLALDH1A1 | |
| SCHEMBL4741046 | 0.64 | POLB (0.59) | KMT2AMEN1CYP2C19MGLLALDH1A1 | |
| SCHEMBL4741482 | 0.64 | POLB (0.59) | KMT2AMEN1CYP2C19MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |