Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556797 | 0.91 | ALDH1A1 (0.46) | CA1CA2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL8556511 | 0.88 | NR4A2 (0.46) | CA1CA2ALDH1A1HSD17B10NR4A2 | |
| SCHEMBL8555990 | 0.84 | NR4A2 (0.62) | CA1CA2ALDH1A1NR4A2KDM4E | |
| SCHEMBL7505599 | 0.83 | CA1 (0.58) | CA1CA2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL7499057 | 0.83 | CA1 (0.58) | CA1CA2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL8555035 | 0.83 | NR4A2 (0.48) | ALDH1A1KMT2ANR4A2KDM4EHPGD | |
| SCHEMBL2117681 | 0.82 | NR4A2 (0.63) | ALDH1A1HSD17B10KMT2ANR4A2MAPT | |
| SCHEMBL8560090 | 0.81 | KDM4E (0.56) | ALDH1A1KMT2ANR4A2KDM4EHPGD | |
| SCHEMBL8555806 | 0.80 | RXRA (0.52) | ALDH1A1KMT2ANR4A2KDM4EHPGD | |
| SCHEMBL8560591 | 0.79 | NR4A2 (0.46) | CA1CA2ALDH1A1HSD17B10NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |