Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.36 |
| ▸ | FEN1 | P39748 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559713 | 0.96 | FABP1 (0.38) | FABP1RXRARXRBNR4A2PTGS1 | |
| SCHEMBL8559922 | 0.90 | ALOX5AP (0.41) | PTGS1PTGS2ALOX5APFEN1MAPT | |
| SCHEMBL8556349 | 0.90 | RXRA (0.38) | RXRARXRBNR4A2ALOX5APFEN1 | |
| SCHEMBL8555763 | 0.88 | RXRA (0.46) | RXRARXRBNR4A2NPC1HPGD | |
| SCHEMBL8553816 | 0.88 | MAPT (0.40) | RXRARXRBNR4A2NPC1HPGD | |
| SCHEMBL8560601 | 0.88 | ALOX5AP (0.41) | PTGS1PTGS2ALOX5APFEN1MAPT | |
| SCHEMBL8561143 | 0.88 | POLB (0.37) | PTGS1PTGS2ALOX5APFEN1MAPT | |
| SCHEMBL8554229 | 0.87 | CDK9 (0.42) | RXRASMN1; SMN2 | |
| SCHEMBL8561430 | 0.86 | ALOX5AP (0.40) | RXRARXRBNR4A2PTGS1PTGS2 | |
| SCHEMBL8555192 | 0.86 | POLB (0.37) | PTGS1PTGS2ALOX5APFEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |