Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553420 | 0.96 | MAPT (0.40) | MAPTALDH1A1LMNAGRM2RXRA | |
| SCHEMBL9025390 | 0.91 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAGRM2RXRA | |
| SCHEMBL8556349 | 0.90 | RXRA (0.38) | MAPTALDH1A1RXRARXRBNR4A2 | |
| SCHEMBL8561449 | 0.90 | RXRA (0.40) | MAPTALDH1A1LMNARXRARXRB | |
| SCHEMBL8555763 | 0.88 | RXRA (0.46) | MAPTALDH1A1LMNARXRARXRB | |
| SCHEMBL8558356 | 0.88 | FABP1 (0.38) | MAPTALDH1A1RXRARXRBNR4A2 | |
| SCHEMBL8556401 | 0.88 | CYP2C9 (0.40) | MAPTALDH1A1LMNARXRARXRB | |
| SCHEMBL8558703 | 0.88 | RXRA (0.49) | MAPTALDH1A1LMNARXRARXRB | |
| SCHEMBL8556147 | 0.87 | MAPT (0.43) | MAPTALDH1A1LMNARXRARXRB | |
| SCHEMBL8556716 | 0.86 | NR4A2 (0.38) | MAPTALDH1A1LMNARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |