SCHEMBL8560061

SCHEMBL8560061

O=C(NC(c1ccccc1)S(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
GAA P10253 2/20 0.51
LMNA P02545 3/20 0.50
HPGD P15428 2/20 0.50
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CTRB1 P17538 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KAT6A Q92794 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
PRMT1 Q99873 1/20 0.46
HPGDS O60760 1/20 0.46
MAPT P10636 1/20 0.46
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4103623 0.81 ALDH1A1 (0.50) ALDH1A1GAALMNAMEN1KMT2A
SCHEMBL4977330 0.81 PTGS2 (0.51) ALDH1A1GAALMNAHPGDMEN1
SCHEMBL14625479 0.79 ALDH1A1 (0.48) ALDH1A1GAALMNACA1CA2
SCHEMBL4256511 0.75 LMNA (0.48) ALDH1A1GAALMNACA1CA2
SCHEMBL15912974 0.74 CNR1 (0.48) ALDH1A1LMNACA1CA2MEN1
SCHEMBL20522011 0.74 CNR1 (0.48) ALDH1A1GAALMNAMEN1KMT2A
SCHEMBL8777246 0.74 CTSK (0.49) CA1MAPTCA12
SCHEMBL5295498 0.73 HSD11B1 (0.46) GAACA1CA2KMT2ACA12
SCHEMBL9961396 0.73 LMNA (0.49) ALDH1A1GAALMNAKMT2ASMN1; SMN2
SCHEMBL31356328 0.73 CASP1 (0.52) ALDH1A1LMNACA1CA2CTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110878030-A Method for synthesizing homoallylic amine compound based on N, S-acetal compound 常州工学院 2020-03-13 CN disclosed
US-5811550-A Process for the preparation of a 1,3-oxazolidine-5-carboxylic acid RHONE-POULENC RORER, S.A. (FR) 1998-09-22 US disclosed
EP-0669915-B1 METHOD FOR THE PREPARATION OF A 1,3-OXAZOLIDINE-5-CARBOXYLIC ACID RHONE POULENC RORER SA (FR) 1997-06-18 EP disclosed
EP-0669915-A1 METHOD FOR THE PREPARATION OF 1,3-OXAZOLIDIN 5-CARBOXYLIC ACID. RHONE POULENC RORER SA (FR) 1995-09-06 EP disclosed
WO-1994012482-A1 METHOD FOR THE PREPARATION OF 1,3-OXAZOLIDIN 5-CARBOXYLIC ACID RHONE-POULENC RORER S.A. (FR) 1994-06-09 WO disclosed