Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 5/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647550 | 0.86 | ACLY (0.37) | MEN1KMT2AWDR5SMN1; SMN2TDP1 | |
| SCHEMBL7261353 | 0.83 | PGR (0.45) | ARSMN1; SMN2TDP1 | |
| SCHEMBL8893381 | 0.83 | PGR (0.39) | MEN1KMT2AARSMN1; SMN2TDP1 | |
| SCHEMBL8906963 | 0.83 | L3MBTL1 (0.36) | MEN1KMT2AARSMN1; SMN2GAA | |
| SCHEMBL7010249 | 0.82 | KMT2A (0.36) | MEN1KMT2AARSMN1; SMN2GAA | |
| SCHEMBL6984955 | 0.81 | BCAT2 (0.36) | MEN1KMT2ASMN1; SMN2GAATDP1 | |
| SCHEMBL8381949 | 0.80 | L3MBTL1 (0.34) | MEN1KMT2ASMN1; SMN2GAATDP1 | |
| SCHEMBL8594988 | 0.80 | L3MBTL1 (0.34) | MEN1KMT2ASMN1; SMN2GAATDP1 | |
| SCHEMBL8890963 | 0.80 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8541763 | 0.79 | GAA (0.34) | MEN1KMT2AARSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843667-A1 | SUBSTITUTED PHENYLURACILS | BAYER AG (DE) | 1998-05-27 | — | — | EP | disclosed |
| EP-0835247-A1 | SUBSTITUTED CARBONYLAMINOPHENYLURACILS | BAYER AG (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997007105-A1 | SUBSTITUTED QUINAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | disclosed |
| WO-1997005118-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | disclosed |