Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261353 | 0.90 | PGR (0.45) | PGRBRD4SMN1; SMN2TDP1AR | |
| SCHEMBL8906963 | 0.84 | L3MBTL1 (0.36) | PGRSMN1; SMN2TDP1L3MBTL1AR | |
| SCHEMBL8560520 | 0.83 | MEN1 (0.34) | SMN1; SMN2TDP1L3MBTL1ARMEN1 | |
| SCHEMBL7029447 | 0.82 | L3MBTL1 (0.31) | PGRL3MBTL1MEN1KMT2A | |
| SCHEMBL6984955 | 0.82 | BCAT2 (0.36) | SMN1; SMN2TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7010249 | 0.81 | KMT2A (0.36) | PGRSMN1; SMN2TDP1L3MBTL1AR | |
| SCHEMBL8381949 | 0.81 | L3MBTL1 (0.34) | PGRSMN1; SMN2TDP1L3MBTL1MEN1 | |
| SCHEMBL8594988 | 0.81 | L3MBTL1 (0.34) | PGRSMN1; SMN2TDP1L3MBTL1MEN1 | |
| SCHEMBL7022860 | 0.80 | BRD4 (0.35) | BRD4 | |
| SCHEMBL8647550 | 0.79 | ACLY (0.37) | SMN1; SMN2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997007105-A1 | SUBSTITUTED QUINAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | disclosed |