Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7951350 | 0.86 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Ethylene SCHEMBL7066311 | 0.80 | HTR6 (0.31) | HTR6HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6916188 | 0.76 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL8407285 | 0.74 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL215793 | 0.71 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL7129602 | 0.69 | PDK2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7939816 | 0.68 | HTR6 (0.32) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL30769736 | 0.67 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Fluoride Ion SCHEMBL6059228 | 0.67 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL30769837 | 0.67 | HTR2A (0.36) | HTR6HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927201-A1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | Hyundai Petrochemical Co., Ltd. (KR) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998009996-A1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | HYUNDAI PETROCHEMICAL CO., LTD. (KR) | 1998-03-12 | — | — | WO | disclosed |