Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8407285

C1=CC([Hf+2](C(c2ccccc2)c2ccccc2)C2c3ccccc3-c3ccccc32)c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6917972 0.88 SIGMAR1 (0.33)
Hydrochloric Acid SCHEMBL6919027 0.81 MEN1 (0.42) MEN1POLBKMT2AATM
Hydrochloric Acid SCHEMBL8560769 0.74 HTR6 (0.31)
Ethylene SCHEMBL7066311 0.74 HTR6 (0.31)
Hydrochloric Acid SCHEMBL6916188 0.71 GPR3 (0.30)
Hydrochloric Acid SCHEMBL7129602 0.69 PDK2 (0.33)
Hydrochloric Acid SCHEMBL7935461 0.66 HTR6 (0.32)
Hydrochloric Acid SCHEMBL7951350 0.66 HTR2A (0.36)
Hydrochloric Acid SCHEMBL215793 0.66 HTR2A (0.36)
Hydrochloric Acid SCHEMBL4479585 0.65 RET (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed