Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL7066311 | 0.81 | HTR6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7126473 | 0.73 | PDK2 (0.32) | PDK2LMNA | |
| SCHEMBL8517920 | 0.72 | PDK2 (0.32) | PDK2LMNA | |
| Hydrochloric Acid SCHEMBL6916188 | 0.72 | GPR3 (0.30) | — | |
| SCHEMBL7132981 | 0.71 | PDK2 (0.32) | PDK2LMNA | |
| Hydrochloric Acid SCHEMBL8407285 | 0.69 | MEN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8560769 | 0.69 | HTR6 (0.31) | — | |
| SCHEMBL4586061 | 0.67 | HTR7 (0.43) | PDK2LMNA | |
| Hydrochloric Acid SCHEMBL6917841 | 0.66 | LMNA (0.39) | PDK2LMNA | |
| Hydrochloric Acid SCHEMBL6919020 | 0.66 | LMNA (0.39) | PDK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530908-B2 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 2003-06-04 | — | — | EP | disclosed |
| EP-0530908-B1 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 1999-04-21 | — | — | EP | disclosed |
| EP-0530908-A1 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM N.V. (NL) | 1993-03-10 | — | — | EP | disclosed |