Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757258 | 0.79 | VCAM1 (0.47) | XDHVCAM1GRIA1GRIA2GRIA3 | |
| SCHEMBL8566378 | 0.77 | ALDH1A1 (0.36) | MAPTHPGDTDP1ALDH1A1ALOX15 | |
| SCHEMBL8568828 | 0.76 | TDP1 (0.48) | MAPTHPGDPOLBTDP1ALDH1A1 | |
| SCHEMBL8562235 | 0.76 | TDP1 (0.48) | MAPTHPGDPOLBTDP1ALDH1A1 | |
| SCHEMBL8566803 | 0.74 | ALOX15 (0.44) | HTTGAAMAPTHPGDTDP1 | |
| SCHEMBL28076647 | 0.73 | MAPT (0.45) | HTTGAAMAPTHPGDTDP1 | |
| SCHEMBL7898980 | 0.71 | HTT (0.44) | HTTGAAMAPTHPGDALDH1A1 | |
| SCHEMBL12466747 | 0.71 | MAPT (0.37) | XDHHTTGAAMAPTHPGD | |
| SCHEMBL23167572 | 0.70 | ALDH1A1 (0.55) | XDHHTTGAAMAPTCYP2C9 | |
| SCHEMBL8567243 | 0.69 | CA2 (0.38) | VCAM1MAPTHPGDCYP2C9APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |