Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561998 | 0.83 | NSD2 (0.60) | NSD2CYP3A4HPGDCYP1A2CYP2C19 | |
| SCHEMBL8568952 | 0.82 | HTT (0.52) | NSD2CYP3A4HPGDCYP1A2CYP2C19 | |
| SCHEMBL8563396 | 0.81 | CES2 (0.39) | HTTKMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL8566566 | 0.79 | CYP1A2 (0.52) | NSD2CYP3A4HPGDCYP1A2CYP2C19 | |
| SCHEMBL8598112 | 0.79 | SMN1; SMN2 (0.43) | CYP3A4HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL8560654 | 0.78 | RAB9A (0.52) | CYP3A4HTTKMT2AEGLN1LMNA | |
| SCHEMBL8597348 | 0.77 | ALDH1A1 (0.45) | HPGDHTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8562887 | 0.76 | BACE1 (0.52) | CYP3A4HPGDCYP1A2CYP2C19HTT | |
| SCHEMBL8560442 | 0.76 | KDM4E (0.45) | CYP3A4CYP1A2CYP2C19KMT2ACYP2D6 | |
| SCHEMBL8565008 | 0.75 | HPGD (0.54) | NSD2CYP3A4HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |