Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557969 | 0.81 | SLC6A2 (0.37) | SLC6A3SLC6A4TACR2SLC6A2LMNA | |
| SCHEMBL8561372 | 0.78 | F2R (0.34) | SLC6A3SLC6A4TACR2SLC6A2LMNA | |
| SCHEMBL8971569 | 0.74 | SLC6A3 (0.43) | SLC6A3SLC6A4MEN1KMT2AOPRK1 | |
| SCHEMBL6422995 | 0.73 | TACR2 (0.58) | TACR2 | |
| SCHEMBL8706751 | 0.72 | SLC6A3 (0.48) | SLC6A3SLC6A4MEN1KMT2ASLC6A2 | |
| SCHEMBL8559300 | 0.71 | F2R (0.52) | SLC6A3SLC6A4TACR2SLC6A2LMNA | |
| SCHEMBL4631301 | 0.71 | MEN1 (0.36) | SLC6A3SLC6A4HTR2CMEN1KMT2A | |
| SCHEMBL4631315 | 0.71 | MEN1 (0.36) | SLC6A3SLC6A4HTR2CMEN1KMT2A | |
| SCHEMBL7307778 | 0.71 | TACR2 (0.59) | TACR2 | |
| SCHEMBL8592272 | 0.71 | SLC6A3 (0.46) | SLC6A3SLC6A4MEN1KMT2ATACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726313-A | Substituted arylaliphatic compounds, method of preparing them and pharmaceutical compositions in which they are present | SANOFI (FR) | 1998-03-10 | — | — | US | disclosed |
| EP-0700386-A1 | NEUROKININ RECEPTOR ANTAGONISTS | SANOFI (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1995026338-A1 | NEUROKININ RECEPTOR ANTAGONISTS | SANOFI (FR) | 1995-10-05 | — | — | WO | disclosed |