Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 8/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563218 | 0.76 | ITGB3 (0.44) | HTR6ITGB3ITGA2B | |
| SCHEMBL8563033 | 0.71 | HTR6 (0.45) | HTR6DRD2 | |
| Hydrochloric Acid SCHEMBL8559384 | 0.70 | HTR6 (0.44) | HTR6 | |
| SCHEMBL8565331 | 0.69 | ITGB3 (0.40) | HTR6ITGB3ITGA2B | |
| SCHEMBL8558617 | 0.68 | HTR6 (0.42) | HTR2CHTR6DRD2 | |
| Hydrochloric Acid SCHEMBL8565218 | 0.67 | HTR6 (0.41) | HTR2CHTR6DRD2 | |
| SCHEMBL8563454 | 0.67 | HTR6 (0.41) | HTR6 | |
| Acetic Acid SCHEMBL8562511 | 0.65 | HTR6 (0.40) | HTR6 | |
| SCHEMBL8563216 | 0.65 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8566149 | 0.64 | HTR6 (0.39) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |