Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563033 | 0.78 | HTR6 (0.45) | HTR6TSHR | |
| SCHEMBL8563850 | 0.78 | ITGB3 (0.52) | ITGB3ITGA2BFAAHACEACE2 | |
| SCHEMBL8558617 | 0.76 | HTR6 (0.42) | HTR6FAAH | |
| SCHEMBL8565326 | 0.73 | ITGB3 (0.40) | ITGB3ITGA2BNOD1FAAHITGAV | |
| Acetic Acid SCHEMBL8562511 | 0.72 | HTR6 (0.40) | HTR6 | |
| SCHEMBL8566149 | 0.71 | HTR6 (0.39) | HTR6PLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL8557446 | 0.70 | HTR6 (0.38) | ITGB3ITGA2BHTR6 | |
| SCHEMBL8563223 | 0.69 | HTR2C (0.36) | ITGB3ITGA2BHTR6 | |
| SCHEMBL8561286 | 0.69 | HTR6 (0.45) | HTR6 | |
| SCHEMBL8417057 | 0.68 | ITGB3 (0.40) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |