Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560113 | 0.89 | ALDH1A1 (0.51) | KMT2AAVPR2AVPR1ATOP1TUBB4A | |
| SCHEMBL8562079 | 0.87 | AVPR2 (0.47) | AVPR2AVPR1ATUBB4ATUBBTUBA3C | |
| SCHEMBL8557684 | 0.85 | AVPR2 (0.51) | PYGLKMT2ASMN1; SMN2AVPR2AVPR1A | |
| SCHEMBL8557390 | 0.84 | AVPR2 (0.52) | AVPR2AVPR1A | |
| SCHEMBL8562249 | 0.83 | AVPR2 (0.45) | PYGLKMT2AMEN1LMNAAVPR2 | |
| SCHEMBL8556903 | 0.83 | AVPR2 (0.53) | PYGLKMT2AMEN1SMN1; SMN2AVPR2 | |
| SCHEMBL8564133 | 0.80 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL8561799 | 0.77 | AVPR2 (0.59) | RAB9ASMN1; SMN2AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8557610 | 0.77 | MAPT (0.52) | KMT2ALMNARAB9ASMN1; SMN2AVPR2 | |
| SCHEMBL8316581 | 0.76 | AVPR2 (0.71) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |