Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562699 | 0.90 | AVPR2 (0.39) | AVPR2AVPR1AITGB1ITGA4RORC | |
| SCHEMBL8564681 | 0.88 | AVPR2 (0.42) | AVPR2AVPR1ATYK2HPGD | |
| SCHEMBL8562616 | 0.86 | ITGB1 (0.40) | AVPR2AVPR1AITGB1ITGA4RORC | |
| SCHEMBL8561799 | 0.84 | AVPR2 (0.59) | AVPR2AVPR1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8561421 | 0.83 | AVPR2 (0.56) | AVPR2AVPR1AOXTR | |
| SCHEMBL8559867 | 0.81 | RAB9A (0.47) | AVPR2AVPR1ARAB9A | |
| SCHEMBL8556908 | 0.81 | RAB9A (0.47) | AVPR2AVPR1ANPC1RAB9A | |
| SCHEMBL8561432 | 0.81 | AVPR2 (0.55) | AVPR2AVPR1ANPC1RAB9ATYK2 | |
| SCHEMBL8562470 | 0.80 | AVPR2 (0.40) | AVPR2AVPR1ATYK2 | |
| SCHEMBL8557787 | 0.80 | PNLIP (0.50) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |