SCHEMBL85653

SCHEMBL85653

CCC(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 4/20 0.36
NR1H3 Q13133 4/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AR P10275 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22623957 0.84 TSHR (0.32) CES1
SCHEMBL24121022 0.82 TSHR (0.30)
SCHEMBL21932503 0.74
SCHEMBL12043851 0.74 NR1H2 (0.30) NR1H2NR1H3
SCHEMBL9476759 0.74
SCHEMBL2629344 0.74
SCHEMBL904330 0.73 FDPS (0.36) NR1H2NR1H3ALDH1A1CES1
SCHEMBL867380 0.72
SCHEMBL5365546 0.72
SCHEMBL4951244 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113827768-B Preparation method of bionic scaffold carrying lysophosphatidic acid nanoparticles 苏州大学附属第二医院 2022-12-09 CN claimed
CN-114555674-A Photosensitive composition and application thereof 普罗米鲁斯有限责任公司 2022-05-27 CN claimed
US-4008139-A Fluorinated compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-02-15 US claimed
WO-2024130341-A1 BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING Aculeus Therapeutics Pty Ltd (AU) 2024-06-27 WO disclosed
US-20230384674-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-20230373937-A1 INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2023-11-23 US disclosed
US-11785845-B2 Composition FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
US-20230259029-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2023-08-17 US disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP disclosed
US-20230229083-A1 PHOTORESIST COMPOSITIONS FOR EUV AND METHODS FOR MANUFACTURING SEMICONDUCTOR DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-20 US disclosed
US-20230229083-A1 PHOTORESIST COMPOSITIONS FOR EUV AND METHODS FOR MANUFACTURING SEMICONDUCTOR DEVICES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-20 US disclosed
US-7186773-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7163982-B2 Process for preparing fluorine-containing polymer and method of forming fine pattern using same DAIKI INDUSTRIES, LTD. (JP) 2007-01-16 US disclosed
US-5319131-A Reacting dimethyl 2-fluoromalonate with formaldehyde to form hydroxymethylated dimethyl 2-flurormalonate, hydrolysis, decarboxylation, dehydration then esterification with a hexafluoroalkylol HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-07 US disclosed
US-5254755-A Solvents, cleaning compounds ALLIED-SIGNAL INC. (US) 1993-10-19 US disclosed
US-5198925-A α-fluoroacrylic acid esters and polymers thereof HOECHST AKTIENGESELLSCHAFT 1993-03-30 US disclosed
WO-1992010454-A1 PARTIALLY FLUORINATED ALKANOLS HAVING A TERTIARY STRUCTURE ALLIED-SIGNAL INC. (US) 1992-06-25 WO disclosed
EP-0203462-A2 Alpha-fluoroacrylic-acid esters and their polymers HOECHST AKTIENGESELLSCHAFT (DE) 1986-12-03 EP disclosed
US-4008139-A Fluorinated compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-02-15 US disclosed
US-4008139-A Fluorinated compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11785845-B2 Composition ADH1A, ADH1C, SLC19A2 NR1H2 794/4885NR1H3 515/4885MEN1 740/4885
US-20230373937-A1 INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY SPNS2, SPCS2, SMN1; SMN2 NR1H2 747/4885NR1H3 1066/4885MEN1 3020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.