SCHEMBL904330

SCHEMBL904330

CCCC(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.36
CES1 P23141 9/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
CES2 O00748 1/20 0.30
LPAR1 Q92633 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2616357 0.82 CES1 (0.39) CES1CES2LPAR1LPAR3
SCHEMBL13325151 0.82 FDPS (0.30) FDPS
SCHEMBL2345427 0.80 CES2 (0.45) FDPSCES1CES2LPAR1LPAR3
SCHEMBL5844557 0.79
SCHEMBL13849607 0.78 CES2 (0.48) FDPSCES1CES2LPAR1LPAR3
SCHEMBL11603249 0.78 CES2 (0.48) FDPSCES1CES2LPAR1LPAR3
SCHEMBL867879 0.73
SCHEMBL85653 0.73 NR1H2 (0.36) CES1NR1H2NR1H3ALDH1A1
SCHEMBL9314294 0.73
SCHEMBL11990036 0.73 ALDH1A1 (0.35) FDPSCES1NR1H2NR1H3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903589-B High-voltage soft polyolefin wire material for new energy automobile and preparation method thereof Suzhou Baima New Material Co.,Ltd. (CN) 2021-08-31 CN claimed
WO-2021076131-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2021-04-22 WO claimed
CN-110903589-A High-voltage soft polyolefin wire material for new energy automobile and preparation method thereof 苏州铂玛新材料有限公司 2020-03-24 CN claimed
US-11785845-B2 Composition FUJIFILM CORPORATION (JP) 2023-10-10 US disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP disclosed
US-11548859-B2 Method for producing (5,S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4Hisoxazol-3-yl]-2-methyl-benzoic acid INTERVET INC. (US) 2023-01-10 US disclosed
WO-2022124182-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING POLYMER AND COMPOSITION セントラル硝子株式会社 2022-06-16 WO disclosed
WO-2022124183-A1 FLUORINE-CONTAINING POLYMER セントラル硝子株式会社 2022-06-16 WO disclosed
US-20220073479-A1 Method for Producing (5,S)-4-[5-(3,5-Dichlorophenyl)-5-(Trifluoromethyl)-4Hisoxazol-3-YL]-2-Methyl-Benzoic Acid INTERVET INC. (US) 2022-03-10 US disclosed
US-20220045283-A1 COMPOSITION FUJIFILM CORPORATION (JP) 2022-02-10 US disclosed
CN-110903589-B High-voltage soft polyolefin wire material for new energy automobile and preparation method thereof Suzhou Baima New Material Co.,Ltd. (CN) 2021-08-31 CN disclosed
US-7306853-B2 Ultra-large scale integrated interconnect structures; forming via and/or line patterns in a curable caged polysilsesquioxane, curing and filling the patterns with a conductor; combines the functions of a photoresist and a conventional low-k dielectric into a single material INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-12-11 US disclosed
US-20070231734-A1 Polymer, a photoacid generator and a dissolution modification agent; patterning; image resolution GLOBALFOUNDRIES U.S. INC. 2007-10-04 US disclosed
US-20070178405-A1 Positive resist composition and method of pattern formation with the same FUJI PHOTO FILM CO., LTD. 2007-08-02 US disclosed
WO-2007062314-A2 HETEROCYCLIC CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-31 WO disclosed
WO-2007062308-A2 HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-05-31 WO disclosed
EP-1757990-A1 RESIN COMPOSITION FOR FORMING FINE PATTERN AND METHOD FOR FORMING FINE PATTERN JSR Corporation (JP) 2007-02-28 EP disclosed
US-20050089800-A1 Photoresist polymer and photoresist composition containing the same HYNIX SEMICONDUCTOR INC. (KR) 2005-04-28 US disclosed
US-5254755-A Solvents, cleaning compounds ALLIED-SIGNAL INC. (US) 1993-10-19 US disclosed
WO-1992010454-A1 PARTIALLY FLUORINATED ALKANOLS HAVING A TERTIARY STRUCTURE ALLIED-SIGNAL INC. (US) 1992-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220045283-A1 COMPOSITION ADH1A, ADH1C, SLC19A2 FDPS 1427/4885CES1 224/4885NR1H2 794/4885
US-11785845-B2 Composition ADH1A, ADH1C, SLC19A2 FDPS 1427/4885CES1 224/4885NR1H2 794/4885
US-20220073479-A1 Method for Producing (5,S)-4-[5-(3,5-Dichlorophenyl)-5-(Trifluoromethyl)-4Hisoxazol-3-YL]-2-Methyl-Benzoic Acid KDM5A, GABRA5, KDM5B FDPS 282/4885CES1 2357/4885NR1H2 3793/4885
US-11548859-B2 Method for producing (5,S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4Hisoxazol-3-yl]-2-methyl-benzoic acid GABRA5, KDM5A, KDM5B FDPS 274/4885CES1 1989/4885NR1H2 3764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.