Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567778 | 0.87 | TACR1 (0.54) | TACR1CD274PDCD1ALDH1A1KMT2A | |
| SCHEMBL8570068 | 0.84 | TACR1 (0.60) | TACR1CD274PDCD1ALDH1A1KMT2A | |
| SCHEMBL8565708 | 0.84 | TACR1 (0.60) | TACR1CD274PDCD1POLQ | |
| SCHEMBL8572409 | 0.77 | TACR1 (0.69) | TACR1POLQ | |
| SCHEMBL31443047 | 0.75 | TRPM8 (0.46) | ALDH1A1KMT2APOLQMEN1TRPM8 | |
| SCHEMBL8720338 | 0.75 | TACR1 (0.57) | TACR1ALDH1A1KMT2AMEN1LTB4R2 | |
| SCHEMBL8566845 | 0.75 | CD274 (0.53) | CD274PDCD1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5883327 | 0.71 | TACR1 (0.54) | TACR1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8720333 | 0.70 | KMT2A (0.51) | CD274PDCD1ALDH1A1KMT2APOLQ | |
| Hydrochloric Acid SCHEMBL5883686 | 0.70 | TACR1 (0.52) | TACR1ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |