Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.69 |
| ▸ | POLQ | O75417 | 10/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871097 | 0.82 | TACR1 (1.00) | TACR1GPBAR1 | |
| SCHEMBL8570068 | 0.81 | TACR1 (0.60) | TACR1POLQGPBAR1 | |
| SCHEMBL8565708 | 0.79 | TACR1 (0.60) | TACR1POLQGPBAR1 | |
| SCHEMBL8567778 | 0.77 | TACR1 (0.54) | TACR1POLQ | |
| SCHEMBL8572406 | 0.77 | POLQ (0.53) | TACR1POLQPTGDR2 | |
| SCHEMBL8566848 | 0.77 | TACR1 (0.53) | TACR1POLQ | |
| SCHEMBL17899450 | 0.72 | RXRA (0.72) | POLQRXRARXRBRXRGPTGDR2 | |
| SCHEMBL31393799 | 0.72 | TACR1 (0.58) | TACR1GPBAR1 | |
| SCHEMBL31393791 | 0.71 | TACR1 (0.54) | TACR1POLQGPBAR1PTGDR2 | |
| SCHEMBL8720338 | 0.71 | TACR1 (0.57) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |