Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298254 | 0.77 | KMT2A (0.54) | L3MBTL1ALDH1A1MAPTTDP1POLB | |
| SCHEMBL8569955 | 0.76 | KMT2A (0.42) | HTTL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL3956436 | 0.76 | NCF1 (0.51) | HTTALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL3272390 | 0.76 | MAPT (0.58) | HTTL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL8566513 | 0.76 | CASP6 (0.44) | HTTL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL8570733 | 0.73 | ALDH1A1 (0.46) | HTTALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL27504823 | 0.73 | KMT2A (0.40) | HTTALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8563618 | 0.73 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL3295785 | 0.73 | ALDH1A1 (0.52) | HTTATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8563462 | 0.72 | CTSB (0.50) | L3MBTL1ALDH1A1KDM4EGRM6GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |