Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568880 | 0.89 | KDM4E (0.33) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8574334 | 0.87 | HIF1A (0.33) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8568404 | 0.80 | IKBKB (0.35) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8573237 | 0.78 | CNR2 (0.33) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8567726 | 0.77 | CNR2 (0.41) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8394301 | 0.75 | HIF1A (0.36) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8567757 | 0.75 | HNF4A (0.46) | HIF1AEPAS1KDM4ELMNAMAPK1 | |
| SCHEMBL8570993 | 0.74 | RARA (0.37) | HIF1AEPAS1CNR2KDM4ELMNA | |
| SCHEMBL8574908 | 0.74 | IKBKB (0.33) | HIF1AEPAS1CNR2LMNAMAPK1 | |
| SCHEMBL8570424 | 0.73 | CNR2 (0.40) | HIF1AEPAS1CNR2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |