Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556880 | 0.80 | LMNA (0.47) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13775158 | 0.74 | HTR3E (0.36) | KDM4EHSP90AA1HTR3EHTR3BHTR1A | |
| SCHEMBL951374 | 0.74 | HTR3E (0.40) | KDM4EL3MBTL1HSP90AA1HTR3EHTR3B | |
| SCHEMBL2592326 | 0.74 | L3MBTL1 (0.42) | KDM4EGAAL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL19480732 | 0.74 | GRIN2D (0.49) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12369780 | 0.74 | NOS3 (0.45) | KDM4EL3MBTL1HTR3EHTR3BHTR1A | |
| SCHEMBL1924873 | 0.74 | ADORA2A (0.45) | KDM4EGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL23754789 | 0.74 | GRIN2D (0.42) | KDM4EGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL19437684 | 0.72 | GRIN2D (0.41) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29508931 | 0.71 | GRIN2D (0.58) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1330650-C | Pyridopyrimidinone compounds, process for their preparation and medicaments containing them | SERVIER LAB (FR) | 2007-08-08 | — | — | CN | disclosed |
| CN-1711260-A | Pyridopyrimidinone compounds, process for their preparation and medicaments containing them | SERVIER LAB (FR) | 2005-12-21 | — | — | CN | disclosed |
| EP-0623620-B1 | 5-HT3 Pyrrolopyrazine derivatives | ADIR (FR) | 1998-09-09 | — | — | EP | disclosed |
| US-5599812-A | ANTISEROTONINE AGENTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |
| EP-0623620-A1 | 5-HT3 Pyrrolopyrazine derivatives | ADIR ET COMPAGNIE (FR) | 1994-11-09 | — | — | EP | disclosed |