Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535622 | 0.76 | MALT1 (0.40) | HSD11B1MAPTKDM4EBRD4LMNA | |
| SCHEMBL13775158 | 0.74 | HTR3E (0.36) | HTR3EHTR3BHTR1AHTR2CHTR3A | |
| SCHEMBL8570392 | 0.74 | KDM4E (0.45) | HTR3EHTR3BHTR1AHTR2CHTR3A | |
| SCHEMBL12369780 | 0.74 | NOS3 (0.45) | HTR3EHTR3BHTR1AHTR2CHTR3A | |
| SCHEMBL2592326 | 0.74 | L3MBTL1 (0.42) | HTR3EHTR3BHTR1AHTR2CHTR3A | |
| SCHEMBL30131549 | 0.74 | MALT1 (0.48) | HSD11B1MAPTKDM4EBRD4LMNA | |
| SCHEMBL12559310 | 0.74 | OPRM1 (0.34) | HSD11B1MALT1TRPA1RPS6KA5 | |
| SCHEMBL8500406 | 0.74 | RPS6KA5 (0.40) | HSD11B1MAPTKDM4EBRD4LMNA | |
| SCHEMBL952863 | 0.74 | NOTUM (0.48) | MAPTKDM4ELMNAMALT1NPC1 | |
| SCHEMBL950222 | 0.74 | RPS6KA5 (0.35) | HSD11B1MAPTKDM4EBRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287721-B | Hydrazide compound and pesticidal use of the same | SUMITOMO CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-7968573-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-1937664-B1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-06-15 | — | — | EP | disclosed |
| EP-1937664-B1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | IKEGAMI HIROSHI | 2011-03-24 | — | — | US | disclosed |
| US-7867949-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-11 | — | — | US | disclosed |
| EP-2251336-A1 | Hydrazide compounds as intermediates of pesticides | Sumitomo Chemical Company, Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| EP-2251336-A1 | Hydrazide compounds as intermediates of pesticides | Sumitomo Chemical Company, Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-7754738-B2 | Pyrazole and pyrrole carboxamide insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754738-B2 | Pyrazole and pyrrole carboxamide insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | FMC CORPORATION | 2007-10-25 | — | — | US | disclosed |
| US-7276601-B2 | Method and preparing fused oxazinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070203201-A1 | Substituted anthranilamides for controlling invertebrate pests | FINKELSTEIN BRUCE L | 2007-08-30 | — | — | US | disclosed |
| WO-2007043677-A9 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007043677-A9 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-06-07 | — | — | WO | disclosed |
| US-7211270-B2 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-01 | — | — | US | disclosed |
| US-7211270-B2 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-01 | — | — | US | disclosed |
| WO-2007043677-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007043677-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-19 | — | — | WO | disclosed |
| US-7199138-B2 | Substituted anthranilamides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | ACHE, H1-2, H1-0 | HTR3E 1880/4885HTR3B 1901/4885HTR1A 1494/4885 |
| US-20070203201-A1 | Substituted anthranilamides for controlling invertebrate pests | ANTXR2, PRXL2A, F9 | HTR3E 4042/4885HTR3B 3643/4885HTR1A 3161/4885 |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | NR2C2, GRK6, NR0B2 | HTR3E 2177/4885HTR3B 803/4885HTR1A 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.