SCHEMBL8570401

SCHEMBL8570401

CC(Cl)(Cl)C(=O)Nc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.61
HPGD P15428 2/20 0.61
ALDH1A1 P00352 2/20 0.61
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
MAPK1 P28482 1/20 0.61
HTT P42858 1/20 0.61
PDK1 Q15118 2/20 0.59
PDK2 Q15119 2/20 0.59
PDK3 Q15120 2/20 0.59
PDK4 Q16654 2/20 0.59
L3MBTL1 Q9Y468 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HSP90AA1 P07900 1/20 0.53
GPR55 Q9Y2T6 1/20 0.53
TP53 P04637 1/20 0.52
EPHX1 P07099 1/20 0.52
TSHR P16473 1/20 0.52
EPHX2 P34913 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10989896 0.88 MAPT (0.61) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL11172475 0.86 MAPT (0.59) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL1764510 0.83 MAPT (0.85) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL83110 0.83 L3MBTL1 (0.78) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL14849461 0.83 PDK1 (0.63) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL11173094 0.82 MAPT (0.56) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL436619 0.81 PDK1 (0.61) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL3129785 0.81 PDK1 (0.67) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL9118485 0.80 MAPT (0.58) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL9697578 0.80 L3MBTL1 (0.55) MAPTHPGDALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023012827-A1 HERBICIDAL COMPOSITION OF PROPANIL, CYHALOFOP BUTYL, AND 2,4-D COROMANDEL INTERNATIONAL LIMITED (IN) 2023-02-09 WO disclosed
CN-108601350-A Herbicide combinations UPL欧洲有限公司 2018-09-28 CN disclosed
CN-108495554-A The appropriate salt of gram elder brother for safe pyroxsulam composition 美国陶氏益农公司 2018-09-04 CN disclosed
CN-108471751-A Herbicidal compositions comprising 4-amino-3-chloro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid, florasulam and pyroxsulam or derivatives thereof 美国陶氏益农公司 2018-08-31 CN disclosed
CN-1052002-C Ether derivatives of tetrahydropyran and tetrahydrofuran, process for their preparation and pharmaceutical compositions containing them ZENECA LTD (GB) 2000-05-03 CN disclosed
WO-1998006780-A1 STABILIZER ADDITIVE FOR AGCHEMICAL TANK MIX ISP INVESTMENTS INC. (US) 1998-02-19 WO disclosed
EP-0793416-A1 ADJUVANT COMPOSITION FOR AGRICULTURAL CHEMICALS AND METHOD FOR ENHANCING THE EFFICACY OF AGRICULTURAL CHEMICAL Kao Corporation (JP) 1997-09-10 EP disclosed
WO-1996016539-A1 ADJUVANT COMPOSITION FOR AGRICULTURAL CHEMICALS AND METHOD FOR ENHANCING THE EFFICACY OF AGRICULTURAL CHEMICAL KAO CORPORATION (JP) 1996-06-06 WO disclosed
CN-1121715-A 4-aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors ZENECA LTD (GB) 1996-05-01 CN disclosed
EP-0515679-A4 PRECIPITATED FLOWABLE CONCENTRATE FORMULATIONS, THEIR PREPARATION AND THEIR AGRICULTURAL USES 1993-06-09 EP disclosed
EP-0471683-A4 BIS-(PYRROLIDONYL ALKYLENE) BIGUANIDES 1992-04-22 EP disclosed
EP-0471683-A1 BIS-(PYRROLIDONYL ALKYLENE) BIGUANIDES GAF CHEMICALS CORPORATION (US) 1992-02-26 EP disclosed
WO-1990013536-A1 BIS-(PYRROLIDONYL ALKYLENE) BIGUANIDES GAF CHEMICALS CORPORATION (US) 1990-11-15 WO disclosed
CN-1036564-A Sulfanilamide (SN) and contain the weedkiller of sulfanilamide (SN) as activeconstituents MITSUBISHI CHEM IND (JP) 1989-10-25 CN disclosed
EP-0318253-A1 Iminophenylthiazolidines, process of preparation, and method of use ICI AMERICAS INC. (US) 1989-05-31 EP disclosed
EP-0226815-A2 A particle growth inhibitor Kao Corporation (JP) 1987-07-01 EP disclosed
EP-0175278-A2 Optical isomer of triazolylpentenols, and their production and use as fungicide herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed
EP-0068295-B1 A NEW HERBICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE A. Nattermann & Cie. GmbH (DE) 1985-08-28 EP disclosed
EP-0124992-A1 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-11-14 EP disclosed
EP-0007719-A2 Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives FBC LIMITED (GB) 1980-02-06 EP disclosed