Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL8401816 | 0.97 | KDM4E (0.62) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL9055511 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL9054050 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL120661 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL1809230 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL29351646 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL1123289 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL9054100 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL65335 | 0.97 | KDM4E (0.68) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL3423511 | 0.94 | KDM4E (0.65) | KDM4EALOX15MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533440-A | POTENTIAL DIFFERENCE BETWEEN REDOX AND REFERENCE ELECTRODES | GENERAL ELECTRIC COMPANY (US) | 1985-08-06 | — | — | US | claimed |
| US-20220193124-A1 | Therapeutic Agent for Flavivirus Infection | NEOPHARMA JAPAN CO., LTD (JP) | 2022-06-23 | — | — | US | disclosed |
| EP-3960241-A1 | THERAPEUTIC AGENT FOR FLAVIVIRUS INFECTION | Neopharma Japan Co., Ltd. (JP) | 2022-03-02 | — | — | EP | disclosed |
| CN-107001529-B | Rheology modifier | 巴斯夫欧洲公司 | 2020-08-25 | — | — | CN | disclosed |
| US-9163103-B2 | Hydrophobically associating copolymers | BASF SE (DE) | 2015-10-20 | — | — | US | disclosed |
| US-9127125-B2 | Process for preparing polyurethane-polyacrylate hybrid dispersions | BASF SE (DE) | 2015-09-08 | — | — | US | disclosed |
| US-20140316035-A1 | HYDROPHOBICALLY ASSOCIATING COPOLYMERS | BASF SE (DE) | 2014-10-23 | — | — | US | disclosed |
| US-8783356-B2 | Hydrophobically associating copolymers | BASF SE (DE) | 2014-07-22 | — | — | US | disclosed |
| CN-102439054-B | Hydrophobically associating copolymers | BASF SE | 2014-05-21 | — | — | CN | disclosed |
| US-20130281636-A1 | PROCESS FOR PREPARING POLYURETHANE-POLYACRYLATE HYBRID DISPERSIONS | BASF SE (DE) | 2013-10-24 | — | — | US | disclosed |
| EP-2432807-A2 | HYDROPHOBICALLY ASSOCIATING COPOLYMERS | BASF SE (DE) | 2012-03-28 | — | — | EP | disclosed |
| US-20100331510-A1 | HYDROPHOBICALLY ASSOCIATING COPOLYMERS | BASF SE (DE) | 2010-12-30 | — | — | US | disclosed |
| WO-2010133527-A2 | HYDROPHOBICALLY ASSOCIATING COPOLYMERS | BASF SE (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-0573927-B1 | Recycling method for photographic processing waste liquid | KONISHIROKU PHOTO IND (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-5573895-A | USING DISTILLATE AS SOLVENT | KONICA CORPORATION (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0471583-B1 | Process for the preparation of salts of iron amino and hydroxy carboxylic acid complexes | HAMPSHIRE CHEMICAL CORP (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0590583-A1 | Multi-part bleach-fix replenisher and use thereof in photographic processing | EASTMAN KODAK COMPANY (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0573927-A1 | Recycling method for photographic processing waste liquid | KONICA CORPORATION (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-5110965-A | Iron chelates from magnetite | W.R. GRACE & CO.-CONN. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0471583-A1 | Process for the preparation of salts of iron amino and hydroxy carboxylic acid complexes | HAMPSHIRE CHEMICAL CORPORATION (US) | 1992-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193124-A1 | Therapeutic Agent for Flavivirus Infection | ALAD, AADAT, AAAS | KDM4E 1332/4885ALOX15 121/4885MAPT 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.