Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571333 | 0.87 | PKM (0.38) | GRM5 | |
| SCHEMBL8573438 | 0.86 | CTSG (0.40) | CHRM4CHRM2 | |
| Hydrochloric Acid SCHEMBL8571485 | 0.85 | CTSG (0.39) | CHRM4CHRM2 | |
| SCHEMBL8571508 | 0.81 | HTR7 (0.37) | OPRM1OPRL1 | |
| SCHEMBL8575669 | 0.81 | CTSG (0.39) | CHRM4CHRM2 | |
| SCHEMBL8572736 | 0.80 | OPRM1 (0.43) | OPRM1OPRL1 | |
| SCHEMBL8575254 | 0.79 | KMT2A (0.37) | CHRM2OPRM1OPRL1 | |
| SCHEMBL8573886 | 0.79 | HDAC1 (0.40) | CHRM4CHRM2OPRM1OPRL1 | |
| SCHEMBL8572795 | 0.78 | ELANE (0.37) | — | |
| SCHEMBL8577063 | 0.76 | AR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |