Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CMA1 | P23946 | 4/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820570 | 0.85 | MEN1 (0.35) | HPGDCMA1DDR1TP53ALDH1A1 | |
| SCHEMBL8607569 | 0.81 | CMA1 (0.35) | HPGDCMA1TP53ALDH1A1MAPT | |
| SCHEMBL8818440 | 0.78 | BCAT1 (0.50) | DDR1ALDH1A1MAPTSMN1; SMN2BCAT2 | |
| SCHEMBL8818687 | 0.76 | HPGD (0.39) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8819833 | 0.76 | KMT2A (0.36) | HPGDALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8570267 | 0.74 | ALDH1A1 (0.46) | HPGDCMA1ALDH1A1MAPTMEN1 | |
| SCHEMBL7470706 | 0.74 | P2RX3 (0.39) | — | |
| SCHEMBL7469280 | 0.74 | HPGD (0.36) | HPGDCMA1ALDH1A1MEN1TSHR | |
| SCHEMBL8819042 | 0.73 | ALDH1A1 (0.39) | HPGDALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL7472788 | 0.72 | RORC (0.42) | TP53ALDH1A1MAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780630-A | 1-METHYL-6-TRIFLUOROMETHYL-2,4(1H,3H)PYRIMIDINEDIONE AS AN INTERMEDIATE FOR HERBICIDES E.G. 1-METHYL-6-TRIFLUOROMETHYL-3-(4-METHOXYPHENYLMETHYL) -2,4(1H,3H)PYRIMIDINEDIONE | FMC CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998008824-A1 | AN INTERMEDIATE USEFUL IN THE SYNTHESIS OF PESTICIDAL URACILS | FMC CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997047607-A1 | HERBICIDAL 3-(SUBSTITUTED-BENZYL)-1-METHYL-6-TRIFLUOROMETHYLURACILS | FMC CORPORATION (US) | 1997-12-18 | — | — | WO | disclosed |
| US-5683966-A | Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils | FMC CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5391541-A | Herbicidal 3-(substituted-benzyl)-1-methyl-6-trifluoromethyluracils | FMC CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| WO-1995004461-A1 | HERBICIDAL 3-(SUBSTITUTED-BENZYL)-1-METHYL-6-TRIFLUOROMETHYLURACILS | FMC CORPORATION (US) | 1995-02-16 | — | — | WO | disclosed |