Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575478 | 0.84 | SLC9A1 (0.49) | — | |
| SCHEMBL8575409 | 0.81 | KDM4E (0.39) | NR1H2NR1H3KDM4EHSD17B10 | |
| SCHEMBL8576511 | 0.80 | LMNA (0.35) | ABCC9ABCC8KCNJ11KCNJ8NR1H2 | |
| SCHEMBL8576925 | 0.78 | CISD1 (0.44) | — | |
| SCHEMBL8059191 | 0.78 | SLC9A1 (0.42) | KDM4EHSD17B10 | |
| SCHEMBL8603912 | 0.77 | CA12 (0.49) | KDM4EHSD17B10 | |
| SCHEMBL8576417 | 0.76 | NOTUM (0.34) | ARKDM4EHSD17B10 | |
| SCHEMBL8571645 | 0.76 | XDH (0.35) | ABCC9ABCC8KCNJ11KCNJ8NR1H2 | |
| SCHEMBL8576497 | 0.75 | KDM4E (0.35) | NR1H2NR1H3KDM4EHSD17B10 | |
| SCHEMBL8043633 | 0.75 | GABRP (0.36) | KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0704431-A2 | Ortho-substituted benzoic acid derivatives | MERCK PATENT GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |