Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520116 | 0.95 | L3MBTL1 (0.33) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL8575396 | 0.85 | CTSG (0.36) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| SCHEMBL8417042 | 0.79 | CTSG (0.35) | CTSGCMA1CACNA1G | |
| Hydrochloric Acid SCHEMBL8571507 | 0.78 | CTSG (0.34) | CTSGCMA1CACNA1G | |
| Hydrochloric Acid SCHEMBL8573565 | 0.78 | CTSG (0.39) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| SCHEMBL8415372 | 0.78 | OPRD1 (0.39) | CTSGCMA1 | |
| SCHEMBL8559521 | 0.77 | TMEM97 (0.39) | CTSGCMA1 | |
| Hydrochloric Acid SCHEMBL8576436 | 0.77 | OPRD1 (0.39) | CTSGCMA1 | |
| SCHEMBL8563033 | 0.77 | HTR6 (0.45) | CTSGCMA1GAAALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8563489 | 0.77 | TMEM97 (0.38) | CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |