Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575598 | 0.84 | CTSS (0.55) | CTSSCTSLCTSKSMN1; SMN2CA5A | |
| SCHEMBL8575593 | 0.84 | CTSS (0.55) | CTSSCTSLCTSKSMN1; SMN2CA5A | |
| SCHEMBL8575447 | 0.81 | CTSS (0.53) | CTSSCTSLCTSKSMN1; SMN2CA5A | |
| Hydrochloric Acid SCHEMBL8571569 | 0.77 | OPRD1 (0.52) | CTSSCTSLCTSKCA5APSMB1 | |
| Hydrochloric Acid SCHEMBL8573389 | 0.77 | OPRD1 (0.52) | CTSSCTSLCTSKCA5APSMB1 | |
| SCHEMBL8573218 | 0.74 | MMP8 (0.56) | MMP8 | |
| SCHEMBL8572721 | 0.74 | MMP8 (0.56) | MMP8 | |
| SCHEMBL8574999 | 0.74 | CDYL2 (0.46) | CTSSCTSLCTSKPSMB1PSMB8 | |
| SCHEMBL8574997 | 0.74 | CDYL2 (0.46) | CTSSCTSLCTSKPSMB1PSMB8 | |
| SCHEMBL8571238 | 0.74 | PSMB1 (0.61) | CTSSCTSKPSMB1PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853713-A | Biologically compatible linear block copolymers of polyalkylene oxide and peptide units | STERLING WINTHROP INC. (US) | 1998-12-29 | — | — | US | disclosed |