Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395303 | 0.86 | EPHX2 (0.42) | CYP4F2CYP4A11CCNA2CDK2CCNA1 | |
| SCHEMBL8414048 | 0.80 | LMNA (0.42) | FAAHCYP4F2CYP4A11ALDH1A1HSD17B10 | |
| SCHEMBL8575697 | 0.79 | NOTUM (0.44) | FAAHALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL7275286 | 0.73 | ITGB3 (0.51) | CYP4F2CYP4A11 | |
| SCHEMBL7275580 | 0.72 | ITGB3 (0.45) | CYP4F2CYP4A11ALDH1A1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL7386679 | 0.72 | ITGB3 (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL19024861 | 0.72 | L3MBTL1 (0.59) | CYP4F2CYP4A11ALDH1A1HSD17B10KDM4E | |
| SCHEMBL4420191 | 0.72 | CA12 (0.50) | CYP4F2CYP4A11ALDH1A1HSD17B10KDM4E | |
| SCHEMBL8558614 | 0.72 | HTR6 (0.38) | FAAHCYP2D6NOTUM | |
| Hydrochloric Acid SCHEMBL8568700 | 0.71 | HTR6 (0.38) | FAAHCYP2D6NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |