Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296973 | 0.77 | RXRA (0.40) | RXRARXRBACHEHDAC4HDAC2 | |
| SCHEMBL232456 | 0.73 | CYP1A2 (0.51) | RXRARXRBACHEHDAC4HDAC2 | |
| SCHEMBL17315931 | 0.72 | BCHE (0.31) | RXRARXRB | |
| SCHEMBL3295540 | 0.71 | HDAC8 (0.41) | RXRARXRBACHEHDAC4HDAC2 | |
| SCHEMBL9802325 | 0.69 | ATM (0.37) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL9432002 | 0.69 | TSHR (0.36) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL7344623 | 0.66 | ATM (0.37) | HDAC4HDAC2HDAC8GAACYP2C19 | |
| SCHEMBL7357616 | 0.66 | PTGS1 (0.56) | RXRARXRBACHEHDAC4HDAC2 | |
| SCHEMBL3235713 | 0.66 | RXRA (0.43) | RXRARXRBACHEHDAC4HDAC2 | |
| SCHEMBL17781751 | 0.65 | RXRA (0.41) | RXRARXRBACHEHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027209-A1 | POLYCATIONIC OLIGOMERS | EMORY UNIVERSITY (US) | 1998-06-25 | — | — | WO | disclosed |