Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 7/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997716 | 0.87 | GHSR (0.33) | GHSR | |
| SCHEMBL8997715 | 0.85 | CPB2 (0.31) | GHSR | |
| SCHEMBL8997695 | 0.81 | P2RY1 (0.37) | — | |
| SCHEMBL8997593 | 0.81 | ALDH1A1 (0.35) | KCNA5ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL8997600 | 0.79 | SYK (0.40) | RPS6KA1KCNA5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8997761 | 0.79 | GHSR (0.33) | GHSR | |
| SCHEMBL8997625 | 0.79 | GHSR (0.37) | RPS6KA1GHSR | |
| SCHEMBL8997604 | 0.77 | GHSR (0.34) | GHSR | |
| SCHEMBL8580708 | 0.76 | GHSR (0.43) | BACE1GAAKCNA5ALDH1A1HPGD | |
| SCHEMBL8997631 | 0.76 | SYK (0.35) | PSMB5GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |