Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PER2 | O15055 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RB1 | P06400 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582700 | 0.72 | TBXA2R (0.42) | MEN1KMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL8793251 | 0.68 | HTR2A (0.44) | MEN1KMT2AHSD17B10HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL8792855 | 0.67 | ALOX15 (0.45) | MEN1KMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL8572018 | 0.62 | CA1 (0.57) | MEN1KMT2AHSD17B10ALDH1A1HTR2A | |
| SCHEMBL22133135 | 0.62 | GPR3 (0.39) | ALDH1A1 | |
| SCHEMBL257566 | 0.62 | GPR3 (0.52) | MEN1KMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL21538077 | 0.61 | CA1 (0.58) | MEN1KMT2AHSD17B10ALDH1A1HTR2A | |
| SCHEMBL20468978 | 0.61 | CA1 (0.58) | MEN1KMT2AHSD17B10ALDH1A1HTR2A | |
| SCHEMBL13877240 | 0.60 | SLC6A4 (0.46) | MEN1KMT2AHSD17B10ALDH1A1HTR2A | |
| SCHEMBL19374171 | 0.60 | ALDH1A1 (0.54) | MEN1KMT2AHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011895-A1 | A METHOD FOR THE PREVENTION OF MIGRAINE | ELI LILLY AND COMPANY (US) | 1998-03-26 | — | — | WO | disclosed |