Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26247007 | 0.72 | TBXA2R (0.55) | TBXA2RPTGDR | |
| SCHEMBL8580723 | 0.72 | MEN1 (0.36) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8572018 | 0.66 | CA1 (0.57) | ALDH1A1MEN1KMT2AHSD17B10CA1 | |
| SCHEMBL5513518 | 0.66 | MEN1 (0.45) | TBXA2RPTGDRHPGDALDH1A1MEN1 | |
| SCHEMBL28328665 | 0.66 | HSD17B10 (0.45) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL19374171 | 0.66 | ALDH1A1 (0.54) | HPGDALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL20468978 | 0.65 | CA1 (0.58) | ALDH1A1MEN1KMT2AHSD17B10CA1 | |
| SCHEMBL21538077 | 0.65 | CA1 (0.58) | ALDH1A1MEN1KMT2AHSD17B10CA1 | |
| SCHEMBL4967660 | 0.65 | KDM4E (0.46) | TBXA2RPTGDRHPGDALDH1A1MEN1 | |
| SCHEMBL13751063 | 0.65 | BRD3 (0.61) | HPGDMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011895-A1 | A METHOD FOR THE PREVENTION OF MIGRAINE | ELI LILLY AND COMPANY (US) | 1998-03-26 | — | — | WO | disclosed |