Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535161 | 0.84 | NCEH1 (0.51) | ALDH1A1MAPTHPGDWDR5MAOB | |
| SCHEMBL8678084 | 0.84 | WDR5 (0.59) | ALDH1A1HPGDWDR5KDM4EHSD17B10 | |
| SCHEMBL4664908 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDWDR5MAOB | |
| SCHEMBL15636146 | 0.80 | LMNA (0.50) | ALDH1A1MAPTHPGDWDR5KDM4E | |
| SCHEMBL21569594 | 0.79 | NCEH1 (0.56) | ALDH1A1MAPTHPGDWDR5MAOB | |
| SCHEMBL8586782 | 0.76 | CA12 (0.51) | ALDH1A1HPGDKDM4E | |
| Formaldehyde SCHEMBL27530553 | 0.75 | LDHA (0.65) | MAPTKDM4ELDHACYP1A2CYP2C9 | |
| SCHEMBL29390177 | 0.74 | LDHA (0.69) | MAPTWDR5KDM4ELDHAMEN1 | |
| SCHEMBL431650 | 0.74 | LDHA (0.69) | MAPTWDR5KDM4ELDHAMEN1 | |
| SCHEMBL975681 | 0.74 | NCEH1 (0.53) | ALDH1A1MAPTHPGDWDR5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |