Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561422 | 0.89 | CTSV (0.36) | CTSVCTSLPDE1CMAPTKMT2A | |
| SCHEMBL8845155 | 0.89 | GHSR (0.42) | CTSLGHSRKMT2APOLBALDH1A1 | |
| SCHEMBL8845267 | 0.89 | GHSR (0.42) | CTSLGHSRKMT2APOLBALDH1A1 | |
| SCHEMBL8580646 | 0.80 | GHSR (0.42) | GHSRMAPTKMT2ANPC1HTT | |
| SCHEMBL8845088 | 0.80 | PDE1C (0.38) | CTSVCTSLPDE1CMAPTKMT2A | |
| SCHEMBL8844917 | 0.79 | GHSR (0.35) | CTSLGHSRMAPTKMT2ANPC1 | |
| SCHEMBL8581093 | 0.79 | GHSR (0.40) | CTSLGHSRMAPTITGA4ITGB7 | |
| SCHEMBL8845103 | 0.78 | GHSR (0.41) | GHSRALDH1A1 | |
| SCHEMBL8844903 | 0.78 | CTSS (0.38) | CTSLGHSRALDH1A1 | |
| SCHEMBL8567143 | 0.77 | CA1 (0.39) | CTSLGHSRMAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644024-A | MIMICS OF PEPTIDE DOMAINS, SEQUENCE DETERMINATION, DRUGS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-01 | — | — | US | disclosed |