Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967660 | 0.80 | KDM4E (0.46) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL4970714 | 0.76 | MEN1 (0.40) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL8793251 | 0.71 | HTR2A (0.44) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL8792855 | 0.70 | ALOX15 (0.45) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL11755532 | 0.69 | CA1 (0.62) | MEN1ALDH1A1KMT2AHSD17B10CA1 | |
| SCHEMBL4968337 | 0.68 | MAPT (0.44) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL9802274 | 0.67 | MEN1 (0.59) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL8582700 | 0.66 | TBXA2R (0.42) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL19374171 | 0.66 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL4969052 | 0.65 | HTR6 (0.49) | MEN1ALDH1A1KMT2AHSD17B10HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819671-A2 | HCV INHIBITORS WITH CARBAZOLE STRUCTURE | SmithKline Beecham Corporation (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006118607-A2 | HCV INHIBITORS WITH CARBAZOLE STRUCTURE | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-09 | — | — | WO | disclosed |