Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583278 | 0.94 | TDP1 (0.47) | TDP1CFTRENPP3ENPP1MEN1 | |
| SCHEMBL3149080 | 0.81 | CA2 (0.47) | TDP1MEN1KMT2AGAAFLT1 | |
| SCHEMBL8732756 | 0.80 | TDP1 (0.42) | TDP1MEN1KMT2ATP53GAA | |
| SCHEMBL8730036 | 0.78 | AOX1 (0.45) | TDP1ENPP3ENPP1MEN1KMT2A | |
| SCHEMBL28514304 | 0.77 | MEN1 (0.54) | TDP1ENPP3ENPP1MEN1KMT2A | |
| SCHEMBL8758117 | 0.76 | GAA (0.47) | TDP1MEN1KMT2ATP53GAA | |
| SCHEMBL8758194 | 0.75 | L3MBTL1 (0.47) | TDP1MEN1KMT2ATP53GAA | |
| SCHEMBL28512466 | 0.74 | CA12 (0.44) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL8729140 | 0.72 | PKM (0.38) | TDP1TP53GAAALDH1A1 | |
| SCHEMBL8730053 | 0.72 | TDP1 (0.43) | TDP1ENPP3ENPP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022480-A1 | PHOSPHORUS CONTAINING ARYLOXY OR ARYLTHIO PROPANOLAMINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1998-05-28 | — | — | WO | disclosed |