Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588933 | 0.96 | HTR2A (0.47) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| Bromide SCHEMBL8590676 | 0.95 | HTR2A (0.47) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL8587433 | 0.95 | HTR2A (0.47) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL8590828 | 0.89 | SLC6A3 (0.54) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL8589313 | 0.89 | SLC6A2 (0.43) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL8589088 | 0.85 | DRD2 (0.45) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL8588378 | 0.84 | HTR2A (0.47) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL8590493 | 0.78 | SLC6A2 (0.43) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL8590773 | 0.78 | SLC6A2 (0.43) | SLC6A3SLC6A2DRD2HTR2AHTR7 | |
| SCHEMBL7753903 | 0.76 | ALDH1A1 (0.51) | DRD2HTR2AHTR7KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852022-A | Antipsychotic agents, composition and method of use | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-5696113-A | Antipsychotic agents, compositions and method of use | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-09 | — | — | US | disclosed |