Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8587433 | 0.99 | HTR2A (0.47) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| Bromide SCHEMBL8590676 | 0.99 | HTR2A (0.47) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8587254 | 0.96 | SLC6A3 (0.45) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8590828 | 0.93 | SLC6A3 (0.54) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8589313 | 0.92 | SLC6A2 (0.43) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8589088 | 0.88 | DRD2 (0.45) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8588378 | 0.87 | HTR2A (0.47) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8590773 | 0.81 | SLC6A2 (0.43) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL8590493 | 0.81 | SLC6A2 (0.43) | HTR2ADRD2HTR7SLC6A2SLC6A3 | |
| SCHEMBL7753903 | 0.79 | ALDH1A1 (0.51) | HTR2ADRD2HTR7KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852022-A | Antipsychotic agents, composition and method of use | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852022-A | Antipsychotic agents, composition and method of use | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0833820-A1 | BENZISOXAZOLE AND INDAZOLE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5696113-A | Antipsychotic agents, compositions and method of use | HOECHST MARION ROUSSEL, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1996039397-A1 | BENZISOXAZOLE AND INDAZOLE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-12-12 | — | — | WO | disclosed |