SCHEMBL8587478

SCHEMBL8587478

O=C1C=C(Nc2ccccc2C(=O)c2ccccc2)C(=O)N1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
APAF1 O14727 1/20 0.42
TDP2 O95551 1/20 0.42
CASP3 P42574 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
AKR1C3 P42330 1/20 0.41
GAA P10253 1/20 0.39
PSMB5 P28074 1/20 0.38
BDKRB1 P46663 2/20 0.37
HSP90AA1 P07900 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5357396 0.73 FABP4 (0.65) KMT2AALDH1A1MAPTAKR1C3PSMB5
SCHEMBL20077657 0.72 ALDH1A1 (0.57) KMT2AALDH1A1MAPTKDM4EAKR1C3
SCHEMBL18498967 0.72 AKR1C3 (0.44) KMT2AALDH1A1MAPTKDM4EAPAF1
SCHEMBL8174226 0.70 KMT2A (0.62) KMT2AALDH1A1MAPTKDM4EAKR1C3
SCHEMBL29587864 0.70 ALDH1A1 (0.48) KMT2AALDH1A1MAPTKDM4EAKR1C3
SCHEMBL20077656 0.69 MAPK13 (0.66) KMT2AALDH1A1MAPTKDM4EAKR1C3
SCHEMBL31541257 0.69 KMT2A (0.66) KMT2AALDH1A1MAPTKDM4EAKR1C3
SCHEMBL4538101 0.69 KMT2A (0.61) KMT2AALDH1A1MAPTAKR1C3GAA
SCHEMBL559678 0.69 KMT2A (0.61) KMT2AALDH1A1MAPTAKR1C3GAA
SCHEMBL2885036 0.69 KMT2A (0.66) KMT2AALDH1A1MAPTKDM4EAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998033764-A1 AMINOBENZOPHENONES AND PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING SAME FIRST CHEMICAL CORPORATION (US) 1998-08-06 WO disclosed