Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619867 | 0.87 | GABBR2 (0.33) | GABBR2GABBR1FDPSLMNA | |
| SCHEMBL6663397 | 0.75 | FDPS (0.38) | FDPSLMNA | |
| SCHEMBL6665485 | 0.67 | FDPS (0.61) | FDPSLMNA | |
| SCHEMBL6674916 | 0.65 | FDPS (0.41) | GABBR2GABBR1FDPSLMNA | |
| SCHEMBL6669236 | 0.64 | FDPS (0.63) | GABBR2GABBR1FDPSLMNA | |
| SCHEMBL6667256 | 0.62 | FDPS (0.39) | FDPSLMNA | |
| SCHEMBL13976468 | 0.62 | LMNA (0.36) | FDPSLMNA | |
| SCHEMBL5054818 | 0.61 | ANPEP (0.44) | GABRR1GABBR2GABBR1FDPSLMNA | |
| SCHEMBL8147759 | 0.61 | FDPS (0.47) | GABBR2GABBR1FDPSLMNA | |
| SCHEMBL19101637 | 0.60 | SMPD1 (0.31) | FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-A4 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0831845-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | Elizanor Biopharmaceuticals, Inc. (US) | 1998-04-01 | — | — | EP | disclosed |