Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588407 | 0.89 | LTA4H (0.47) | ALDH1A1CYP2D6CYP1A2NPSR1CHRNA7 | |
| SCHEMBL8587389 | 0.88 | ALDH1A1 (0.43) | GAAALDH1A1POLBCYP2D6CYP1A2 | |
| SCHEMBL8590752 | 0.86 | TSHR (0.45) | ALDH1A1CYP2D6CYP1A2NPSR1CHRNA7 | |
| SCHEMBL8587396 | 0.86 | FFAR2 (0.45) | ALDH1A1CYP2D6CYP1A2NPSR1CHRNA7 | |
| SCHEMBL8590761 | 0.86 | MEN1 (0.50) | GAAALDH1A1CYP2D6CYP1A2NPSR1 | |
| SCHEMBL8589194 | 0.83 | GAA (0.48) | GAAALDH1A1POLBNPSR1KDM4E | |
| SCHEMBL8589108 | 0.82 | CHRNA7 (0.42) | ALDH1A1CYP2D6CYP1A2CHRNA7CYP3A4 | |
| SCHEMBL8587669 | 0.81 | CYP2D6 (0.53) | ALDH1A1CYP2D6CYP1A2HPGDCYP3A4 | |
| SCHEMBL8589515 | 0.80 | CYP2D6 (0.46) | CYP2D6CYP1A2CHRNA7CYP3A4CYP2A6 | |
| SCHEMBL8586522 | 0.78 | LMNA (0.52) | ALDH1A1CYP1A2NPSR1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |