Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257119 | 0.92 | POLB (0.40) | SMN1; SMN2POLBAOC3NPC1RAB9A | |
| SCHEMBL9131392 | 0.88 | POLB (0.38) | SMN1; SMN2POLBAOC3NPC1RAB9A | |
| SCHEMBL4888374 | 0.78 | POLB (0.39) | SMN1; SMN2POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL2564080 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL29954781 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL27357705 | 0.76 | POLB (0.38) | SMN1; SMN2POLBAOC3NPC1RAB9A | |
| SCHEMBL8596999 | 0.76 | POLB (0.38) | SMN1; SMN2POLBAOC3NPC1RAB9A | |
| SCHEMBL6188044 | 0.76 | GRM5 (0.39) | SMN1; SMN2POLBAOC3NPC1RAB9A | |
| SCHEMBL4990435 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL8788397 | 0.74 | NPSR1 (0.55) | SMN1; SMN2NPC1RAB9AL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593332-B1 | Phenylborinic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1998-01-14 | — | — | EP | claimed |
| US-5382672-A | Preparation of derivatives of benzeneborinic acid | SYNTHELABO (FR) | 1995-01-17 | — | — | US | claimed |
| US-5278312-A | Derivatives of benzeneborinic acid, preparation thereof and use thereof as synthetic intermediates | SYNTHELABO (FR) | 1994-01-11 | — | — | US | claimed |
| JP-6192240-A | — | — | None | — | — | JP | disclosed |
| EP-2886548-A1 | METHOD FOR PRODUCING BORINIC ACID DERIVATIVE, AND NOVEL BORINIC ACID DERIVATIVE | Manac Inc. (JP) | 2015-06-24 | — | — | EP | disclosed |
| US-20150105562-A1 | METHOD FOR PREPARING BORINIC ACID DERIVATIVES AND NOVEL BORINIC ACID DERIVATIVES | MANAC INC. (JP) | 2015-04-16 | — | — | US | disclosed |
| US-5382672-A | Preparation of derivatives of benzeneborinic acid | SYNTHELABO (FR) | 1995-01-17 | — | — | US | disclosed |
| JP-H06192240-A | BENZENEBORINIC ACID DERIVATIVE, PREPARATION THEREOF AND USE THEREOF AS SYNTHETIC INTERMEDIATE | SYNTHELABO SA | 1994-07-12 | — | — | JP | disclosed |
| US-5278312-A | Derivatives of benzeneborinic acid, preparation thereof and use thereof as synthetic intermediates | SYNTHELABO (FR) | 1994-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105562-A1 | METHOD FOR PREPARING BORINIC ACID DERIVATIVES AND NOVEL BORINIC ACID DERIVATIVES | ADORA2B, TPSAB1, ACVR2B | SMN1; SMN2 1879/4885POLB 1316/4885AOC3 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.